Comparison of high glomerular filtration rate thresholds for identifying hyperfiltration

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Estimated glomerular filtration rate.

The recent article about estimated glomerular filtration rate (GFR) by Levey and colleagues (1) is remarkable. The authors suggest that the new equation may still have some bias and especially may have less precision in patients with GFRs greater than 60 mL/min per 1.73 m 2 . This is even more important if the GFR is greater than 90 mL/min per 1.73 m 2 . In the paper's Methods section, Levey an...

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How Measuring Glomerular Filtration Rate? Comparison of Reference Methods

Glomerular filtration rate (GFR) is considered as the best way to assess global renal function (Gaspari et al., 1997; Stevens & Levey, 2009). Even if GFR estimations (based on creatinineor cystatin C-based equations) are most often used (see Table 1)(Cockcroft & Gault, 1976; Levey et al., 1999; Levey et al., 2006; Levey et al., 2009), measuring “true” GFR is still important in clinical practice...

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Performance comparison of estimated glomerular filtration rate equations

The glomerular filtration rate (GFR) cannot be measured by direct means, but can be assessed by urinary clearance of exogenous filtration markers such as inulin, iohexol, or iothalamate [1,2]. However, for several reasons, direct GFR measurements are not suitable for use in routine laboratory settings. Hence, it is more appropriate to derive an estimated GFR (eGFR) from various equations. Howev...

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Are glomerular filtration rate estimations necessary before high dose methotrexate?

Glomerular filtration rates (GFR) were estimated in 168 children (227 estimates) before treatment for haematological malignancies with high dose, intravenous methotrexate. Clinical management was altered on the basis of GFR in only two cases, both of whom had tumour lysis syndrome. Routine estimations of GFR do not contribute to management.

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2018

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfy332